AJHI2202 - CME/CMLE - The Histopathology of Anorectal Neisseria gonorrhoeae Infection-The Histopathology of Anorectal Neisseria gonorrhoeae Infection

The Histopathology of Anorectal Neisseria gonorrhoeae Infection

Pdf Summary

The study focused on the histopathology of anorectal Neisseria gonorrhoeae infection, emphasizing the importance of prompt diagnosis and treatment to prevent complications such as infertility and septic joints. The research analyzed biopsy specimens from eight male patients with confirmed gonococcal infection, noting mild acute inflammation as a common feature, with lymphoid aggregates seen in most cases. Intense lymphoplasmacytic infiltration was rare and typically associated with concurrent infections like cytomegalovirus. The study highlighted the challenges in diagnosing anorectal gonorrhea due to its often asymptomatic nature, necessitating a high index of suspicion based on risk factors. Biopsies showed nonspecific findings, making it essential for pathologists to recommend additional infectious workup when subtle changes are present, even without specific symptoms. The report stressed the need for a complete clinical history, especially in high-risk individuals like men who have sex with men, to guide appropriate diagnostic testing. The study contributes valuable insights into the histological features of anorectal gonorrhea, underscoring the importance of considering sexually transmitted infections in the differential diagnosis of anorectal pathology and prompting further investigation when suggestive histologic changes are observed.

Keywords

histopathology

Neisseria gonorrhoeae

anorectal infection

diagnosis

treatment

complications

infertility

septic joints

biopsy specimens

gonococcal infection