AJIM2302 - CME/CMLE - Use of Clinical Decision Support to Improve the Laboratory Evaluation of Monoclonal Gammopathies-Use of Clinical Decision Support to Improve the Laboratory Evaluation of Monoclonal Gammopathies

Use of Clinical Decision Support to Improve the Laboratory Evaluation of Monoclonal Gammopathies

Pdf Summary

The study examined the impact of a clinical decision support (CDS) alert on enhancing compliance with guidelines for diagnosing monoclonal gammopathies by promoting serum free light chain (sFLC) testing. By triggering alerts when serum protein electrophoresis (SPEP) was ordered without sFLC, the study significantly increased co-ordering of sFLC tests, identifying abnormalities in 28.9% of patients with new diagnoses. Providers in inpatient settings and specialities like internal medicine and primary care showed higher compliance rates. The alert improved diagnostic evaluation, identified high-risk patients, and facilitated timely clinical interventions. Challenges included varying compliance rates among providers and the need for tailored alert strategies. Despite challenges with ICD-10 coding and pandemic-related disruptions, the study emphasized the alert system's impact on guideline adherence and patient care for monoclonal gammopathy cases. The study suggested adjusting alert triggers based on ordering indications and provider-centric alert strategies to enhance effectiveness and reduce alert fatigue. Overall, the alert system showed promise in enhancing guideline adherence, diagnosing, and managing monoclonal gammopathies, with recommendations for future research and optimization of testing algorithms in healthcare settings.

Keywords

clinical decision support alert

guidelines compliance

monoclonal gammopathies

serum free light chain testing

serum protein electrophoresis

co-ordering tests

diagnostic evaluation

high-risk patients

alert system impact

provider-centric alert strategies