AJMB2301 - CME/CMLE - Kidney Pathology of Tropical and Non-Tropical Infectious Diseases in the Pediatric Population-Renal Pathology of Tropical and Non-Tropical Infectious Diseases in the Pediatric Population

Renal Pathology of Tropical and Non-Tropical Infectious Diseases in the Pediatric Population

Pdf Summary

This review article focuses on the pathology of tropical and nontropical infectious diseases affecting the kidneys of children. Infectious diseases impacting the kidneys through indirect pathways, like immune responses, are more common. Direct pathways, where the pathogen directly invades the kidneys, are less known, occurring in immunocompromised or tropical regions. Six diseases were reviewed: renal cryptococcosis (direct pathway), schistosomiasis, and dengue fever (dual direct and indirect pathways), and congenital syphilis, visceral leishmaniasis, and Chagas disease (indirect pathways). These diseases exhibit unique kidney pathology, involving granulomatous inflammation, glomerular lesions, and interstitial fibrosis. Diagnosis involves clinical manifestations and laboratory tests, with treatments tailored to manage each condition effectively. Awareness of these infections is crucial for pediatric nephrologists, nephropathologists, and other pathologists for accurate diagnosis and management. The review emphasizes the importance of understanding the direct and indirect mechanisms of kidney injury in infectious diseases, especially in pediatric populations, to optimize patient care and outcomes.

Keywords

infectious diseases

kidney pathology

renal cryptococcosis

schistosomiasis

dengue fever

congenital syphilis

visceral leishmaniasis

Chagas disease

pediatric nephrology

immune responses