LQCL2203 - CMLE - INVESTIGATION OF PSEUDOHYPERPHOSPHATEMIA IN A PATIENT WITH MULTIPLE MYELOMA-INVESTIGATION OF PSEUDOHYPERPHOSPHATEMIA IN A PATIENT WITH MULTIPLE MYELOMA

INVESTIGATION OF PSEUDOHYPERPHOSPHATEMIA IN A PATIENT WITH MULTIPLE MYELOMA

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The document discusses a case study focusing on investigating pseudohyperphosphatemia in a patient with multiple myeloma. The patient's fluctuating phosphate levels were noted, prompting questions about possible interferences and the accuracy of results. The investigation highlighted the role of autoverification, including delta check quality rules, in detecting and resolving potential errors. It emphasized the importance of quality mechanisms in laboratories to prevent reporting incorrect results. Various causes of hyperphosphatemia and hypophosphatemia were outlined, with an emphasis on the regulation of phosphate in the body. Methods to mitigate interference from monoclonal proteins, such as ultrafiltration and dilution, were discussed in the context of ensuring accurate measurements. Overall, the case study underscores the significance of utilizing quality control measures like delta checks in the laboratory to enhance patient care and avoid unnecessary procedures based on erroneous results.

Keywords

pseudohyperphosphatemia

multiple myeloma

fluctuating phosphate levels

autoverification

delta check quality rules

hyperphosphatemia

hypophosphatemia

regulation of phosphate

monoclonal proteins

quality control measures