LQCL2210 - CMLE - EVOLVING CLINICAL MICROBIOLOGY PRACTICES FOR CANDIDA AURIS-EVOLVING CLINICAL MICROBIOLOGY PRACTICES FOR CANDIDA AURIS

EVOLVING CLINICAL MICROBIOLOGY PRACTICES FOR CANDIDA AURIS

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In the document, "ASCP LabQ 2022 Microbiology," the focus is on Candida auris, a pathogenic yeast causing invasive fungal infections. The paper details the epidemiology, transmission, laboratory identification, susceptibility testing, and treatment considerations for C auris. It discusses a case of a 65-year-old man with abdominal issues who developed a C auris infection during hospitalization. The importance of accurate identification using specific laboratory techniques like MALDI-TOF MS is highlighted. The document emphasizes the need for antifungal susceptibility testing, although interpretive breakpoints are yet to be defined, and mentions the recommendation of echinocandins for empiric treatment due to multidrug resistance observed in C auris isolates. It further notes the challenges in differentiating C auris from other Candida species, as conventional methods may misidentify it. The paper underlines the public health concern posed by C auris due to its transmissibility and persistence, stressing the need for infection control measures. Lastly, the document provides insights on the evolving practices in clinical microbiology for managing C auris infections, including rapid molecular testing for faster identification. It also references significant sources and raises questions to reinforce key points discussed in the text.

Keywords

Candida auris

invasive fungal infections

epidemiology

transmission

laboratory identification

susceptibility testing

treatment considerations

antifungal susceptibility testing

echinocandins

infection control measures