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LQCL2214 - CMLE - USING MALDI-TOF TO IDENTIFY EIKE ...
USING MALDI-TOF TO IDENTIFY EIKENELLA CORRODENS IN ...
USING MALDI-TOF TO IDENTIFY EIKENELLA CORRODENS IN A CASE OF INFECTIVE ENDOCARDITIS
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Pdf Summary
The document discusses Molecular Diagnostics focusing on identifying infective endocarditis and the causative organism Eikenella corrodens. A case study of a 17-year-old diabetic patient with symptoms of fever, chills, and increased heart rate is used to exemplify the diagnostic process. Traditional methods for identifying bacteria and challenges in diagnosing fastidious organisms like Eikenella corrodens are highlighted. MALDI-TOF technology is described as a tool to aid in rapid and accurate identification of challenging microorganisms. The method involves ionizing particles and comparing their mass-to-charge ratio for identification. The benefits of MALDI-TOF in reducing turnaround times and improving patient outcomes are emphasized. The case study concludes that MALDI-TOF successfully identified Eikenella corrodens, allowing for the appropriate antibiotic treatment. The summary emphasizes the importance of quick identification to improve prognosis in infectious diseases like infective endocarditis. It also mentions that only a single colony is required for MALDI-TOF identification and the technique is beneficial for fastidious and challenging organisms. The document also contains CMLE questions to reinforce the key concepts discussed throughout the text.
Keywords
Molecular Diagnostics
Infective Endocarditis
Eikenella corrodens
Case Study
Diabetic Patient
MALDI-TOF Technology
Ionizing Particles
Mass-to-Charge Ratio
Turnaround Times
Infectious Diseases
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