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CSCC2405 - CME/CMLE - Mouse in the Mix: Human Anti-Mouse Antibody Interference in Clinical Assays
Course Description

Faculty/Authors

Catherine Omosule, PhD, DABCC
Medical And Scientific Research Centre 
University Of Ghana Medical Centre 

Patrick Seidu, MBCHB 
Department of Internal Medicine 
Korle-Bu Teaching Hospital 
Accra, Ghana 

CME or CMLE Credit: 2.0
Estimated Completion Time: 2 hours
Format: Online Educational Activity and Post Exam

Physician Competencies: Patient Care, Medical Knowledge

Eligibility for CME/CMLE credit: Max three attempts. You will have a maximum of three attempts to meet the following criteria:

  • Module ≥80% = CME credit
  • Module <80% = No CME credit, after a maximum of three attempts

Default Credit Type: None (You must meet the eligibility requirements in order to obtain CME credit.)

Accreditation Statement:
The American Society for Clinical Pathology (ASCP) is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education (CME) for physicians. This activity has been planned and implemented in accordance with the Essential Areas and Policies of the Accreditation Council for Continuing Medical Education (ACCME).

Credit Designation Statement: The American Society for Clinical Pathology (ASCP) designates this enduring material for a maximum of 2 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Instructions

  1. Review the Technical Considerations.
  2. Click Go to Course to view an overview of the modules in this course.
  3. Click Access to begin the course.
  4. Choose the CME Activity to earn CME credit or the CMLE Activity to earn CMLE credit.

To claim CME credit for the exercise, do the following:

  1. Review the Educational Activity.
  2. Complete and submit the Post Exam. You will have a maximum of three attempts to obtain the required score. You will be notified if you have met the credit requirements after each attempt.
  3. Submit the course Evaluation.
  4. Enter the maximum number of credits offered and click Claim CME to register credit.

To claim CMLE credit for the exercise, do the following:

  1. Review the Educational Activity.
  2. Complete and submit the Post Exam.
  3. Submit the course Evaluation.
  4. Enter the maximum number of credits offered and click Claim CME to register credit.
Faculty Disclosures​ 

Technical Considerations

Release Date: 10/31/2024 
Review Date:
Expiration Date: 12/31/2026 

Learning Objectives
Upon completion of this activity, you will be able to:
  • explain the etiology and development of heterophile antibodies and human anti-mouse antibodies (HAMA); 

  • recognize clinical situations that merit evaluation of HAMA in patients; 

  • formulate strategies to test for and overcome heterophile antibody interference on immunoassays; and 

  • describe the analytic challenges posed by HAMA interference in immunoassays, including its potential impact on diagnostic accuracy and patient care. 

Summary
Availability: On-Demand
Credit Offered:
2 CME Credits
2 CMLE Credits
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