Faculty/Authors

Jun Liu, MD, PhD  
Wen Lu, MD 

Department of Pathology
Brigham and Women’s Hospital
Boston, Massachusetts 

Kevin Park, BS 

Department of Medicine
University of California Los Angeles 

CME or CMLE Credit: 2.0
Estimated Completion Time: 2 hours
Format: Online Educational Activity and Post Exam

Physician Competencies: Patient Care, Medical Knowledge

Eligibility for CME/CMLE credit: Max three attempts. You will have a maximum of three attempts to meet the following criteria:

• Module ≥80% = CME credit
• Module <80% = No CME credit, after a maximum of three attempts

Default Credit Type: None (You must meet the eligibility requirements in order to obtain CME credit.)

Accreditation Statement: The American Society for Clinical Pathology (ASCP) is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education (CME) for physicians. This activity has been planned and implemented in accordance with the Essential Areas and Policies of the Accreditation Council for Continuing Medical Education (ACCME).

Credit Designation Statement: The American Society for Clinical Pathology (ASCP) designates this enduring material for a maximum of 2 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Instructions

1. Review the Technical Considerations.
2. Click Go to Course to view an overview of the modules in this course.
3. Click Access to begin the course.
4. Choose the CME Activity to earn CME credit or the CMLE Activity to earn CMLE credit.

To claim CME credit for the exercise, do the following:

1. Review the Educational Activity.
2. Complete and submit the Post Exam. You will have a maximum of three attempts to obtain the required score. You will be notified if you have met the credit requirements after each attempt.
3. Submit the course Evaluation.
4. Enter the maximum number of credits offered and click Claim CME to register credit.

To claim CMLE credit for the exercise, do the following:

1. Review the Educational Activity.
2. Complete and submit the Post Exam.
3. Submit the course Evaluation.
4. Enter the maximum number of credits offered and click Claim CME to register credit.

Faculty Disclosures

Technical Considerations

Release Date: 10/28/2022
Review Date:
Expiration Date: 12/31/2024

• explain the pathophysiology of thalassemia; 

• explain the genetic underpinning of thalassemia; 

• differentiate transfusion-dependent thalassemia (TDT) from non–transfusion-dependent thalassemia (NTDT); 

• explain why the pretransfusion hemoglobin targets may vary for patients with TDT; 

•  discuss appropriate modifications of pretransfusion hemoglobin targets for patients with severe symptoms and comorbidities; and 

• explain the risks of transfusion therapy in patients with TDT and NTDT, such as iron overload and alloimmunization.