Activity Overview  

This activity is designed to help pathologists and laboratory professionals gain an understanding of the challenges in diagnosing HPV-negative cervical cancers and precancers, including the limitations of current testing methods and potential strategies for accurate identification. 

Course topics include: 

• Reasons for negative HPV test results in the context of cervical cancer diagnosis 

•  Limitations of current HPV testing methods and potential strategies to ensure accurate identification of HPV-negative cervical cancers and precancers 

• Clinical implications of HPV-negative cervical cancers and precancers in patient surveillance and management 

Target Audience 
This activity has been designed to meet the educational needs of pathologists and laboratory professionals.    

Faculty/Authors

Chengquan Zhao, MD
Professor and Director of Cytopathology, Department of Pathology
Magee-Womens Hospital of University of Pittsburgh Medical Center
Pittsburgh, PA  

Physician's Competency: Patient Care, Medical Knowledge, Practice-Based Learning and Improvement 

CME/CMLE Credit: 0.25
Estimated Completion Time: 0.25 hour
Format: Online educational activity

Accreditation Statement
The American Society for Clinical Pathology (ASCP) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education (CME) for physicians. 

Credit Designation Statement

The ASCP designates this internet live activity for a maximum of .25 AMA PRA Category 1 Credit(s)™. Physicians should claim only credit commensurate with the extent of their participation in the activity. 

ASCP designates this live activity for a maximum of .25 CMLE credit.  This activity meets CMP and state re-licensure requirements for laboratory personnel. 

For questions regarding CME credit, please contact ASCP Customer Service at 1-800-267-2727, option 2, in the US & Canada or internationally at access code + 3-1-312-541-4890. Monday-Friday, 8am-5pm CT.

Method of Participation

To complete the activity and receive credit, the participant must participate in the online program. CME certificates will be provided on-line.  

Commercial Support 

This activity is supported by an independent educational grant from Hologic.   

Instructions

To claim CME/CMLE credit for the exercise, do the following:

1. Review the Technical Considerations.
2. Click Go to Content and click the first module of the course.
3. Complete the Demographic Survey.
4. Complete the Pre-Test.
5. Review the Educational Activity.
6. Complete and submit the Post Exam. You will have a maximum of three attempts to obtain the required score. You will be notified if you have met the credit requirements after each attempt.
7. Submit the course Evaluation.
8. Enter the maximum number of credits offered and click Claim CME/CMLE to register credit.

Upon completion of this activity, you will be able to:

• Describe the epidemiology and clinical significance of HPV-negative cervical cancers and precancers 

• Discuss the histopathological features of HPV-negative cervical cancers and precancerous lesions 

• Examine the reasons for negative HPV test results in the context of cervical cancer diagnosis 

• Explain the limitations of current HPV testing methods and potential strategies to ensure accurate identification of HPV-negative cervical cancers and precancers 

• Describe the clinical implications of HPV-negative cervical cancers and precancers in patient surveillance and management