Considerations Around Establishing a PD-L1 Laboratory Developed Test (LDT)
 
This activity is designed to help pathologists and laboratory professionals understand the key consideration when establishing a PD-L1 Laboratory Developed Test (LDT). Panelists will discuss their experiences with an LDT and explain what is involved with validation and scoring different types of cancers.
Provided by the American Society for Clinical Pathology in partnership with Q Synthesis LLC.
 
The activity offers 0.5 CME/CMLE credit.
 
Target Audience
This activity has been designed to meet the educational needs of pathologists and laboratory professionals diagnosing cancer.
 
Activity Agenda

• Introductions
• Review what is involved with establishing and validating a PD-L1 laboratory developed test (LDT)
• Scoring systems
• Panel discussion: experiences with a PD-L1 LDT
• Summary of key takeaways

Faculty/Authors

Yin P. (Rex) Hung, M.D., Ph.D.
Assistant Pathologist, Massachusetts General Hospital
Assistant Professor in Pathology, Harvard Medical School
Boston, Massachusetts
 
Mamatha Chivukula, MD, FASCP
Pathologist, Mills-Peninsula Medical Center, Sutter Health
Burlingame, California
 
Jefree J. Schulte, MD
Assistant Professor, Department of Pathology and Laboratory Medicine
University of Wisconsin-Madison School of Medicine and Public Health
Madison, Wisconsin
 
Joseph Kim, MD, MPH, MBA
President, Q Synthesis LLC r and Director, Translational Research/Pathology Shared Resource of Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 

Accreditation Statement
The American Society for Clinical Pathology (ASCP) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education (CME) for physicians.

Physician's Competency: Patient Care, Medical Knowledge, Practice-Based Learning and Improvement

CME/CMLE Credit: 0.5
Estimated Completion Time: 0.5 hour
Format: Online educational activity

Credit Designation Statement
The American Society for Clinical Pathology (ASCP) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education (CME) for physicians.
 
The ASCP designates this activity for a maximum of 0.5 AMA PRA Category 1 Credit(s)™. Physicians should claim only credit commensurate with the extent of their participation in the activity.
 
ASCP designates this activity for a maximum of 0.5 CMLE credit.  This activity meets CMP and state re-licensure requirements for laboratory personnel.
 
For questions regarding CME credit, please contact ASCP Customer Service at 1-800-267-2727, during normal business hours: Monday through Friday, 8 a.m. to 6 p.m. Eastern Time 

Method of Participation
To complete the activity and receive credit, the participant must complete the online activity. CME certificates will be provided onlin 
 
Commercial Support
This activity is funded by an independent educational grant from Merck. 

Instructions

To claim CME/CMLE credit for the exercise, do the following:

1. Review the Technical Considerations.
2. Click Go to Content and click the first module of the course.
3. Complete the Demographic Survey.
4. Complete the Pre-Test.
5. Review the Educational Activity.
6. Complete and submit the Post Exam. You will have a maximum of three attempts to obtain the required score. You will be notified if you have met the credit requirements after each attempt.
7. Submit the course Evaluation.
8. Enter the maximum number of credits offered and click Claim CME/CMLE to register credit.

Upon completion of this activity, you will be able to:

• Describe how laboratories are establishing a PD-L1 laboratory developed test (LDT).

• List the key considerations around establishing a PD-L1 LDT.

• Discuss some potential limitations when using a PD-L1 LDT.