Course Description

Multidisciplinary approach to diagnosis and biomarker testing in gastrointestinal cancer 

This 60-minute on-demand webcast highlights important and practice-changing developments in gastrointestinal biomarker testing and treatment, including new clinical data with immediate implications for patient care. Using a case-based approach, an expert GI pathologist and oncologist will help you learn optimal testing, interpreting findings, individualized treatment, and sequencing strategies for gastrointestinal cancers. 

Topics include: 

1. Biomarkers and the use of molecular testing to guide therapy selection in patients with advanced colorectal, pancreatic, biliary, gastric, esophageal, and gastroesophageal junction cancers, such as: 
   • BRAF V600E, BRCA1/2, HER2/HER3, BRAF V600E, IDH1, and FGFR2 
   • Tumor agnostic biomarkers, such as MMR/MSI, NTRK, and TMB
   • Emerging biomarkers 

2. Emerging assays in GI cancers, such as liquid biopsy  

This webcast includes case discussions, polling questions, and a Q&A session for you to get answers from the experts in real time. 

The activity offers 1.0 CME/CMLE credi

Faculty/Authors

Wei Jiang, MD, PhD
Associate Professor
Director, Translational Research/Pathology
Shared Resource of Sidney Kimmel Cancer Center
Thomas Jefferson University
Philadelphia, PA 

Atrayee Basu-Mallick, MD
Associate Professor
Medical Oncology
Jefferson Health/Jefferson University Hospitals
Philadelphia, PA 

Physician's Competency: Patient Care, Medical Knowledge, Practice-Based Learning and Improvement

CME/CMLE Credit: 1.0
Estimated Completion Time: 1.0 hour
Format: Online educational activity

Credit Designation Statement

The ASCP designates this internet activity for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only credit commensurate with the extent of their participation in the activity. 

ASCP designates this internet activity for a maximum of 1.0 CMLE credit.  This activity meets CMP and state re-licensure requirements for laboratory personnel. 

For questions regarding CME credit, please contact ASCP Customer Service at 1-800-267-2727, during normal business hours: Monday through Friday, 8 a.m. to 6 p.m. Eastern Time 

Method of Participation
To complete the activity and receive credit, the participant must complete the online activity. CME certificates will be provided online. 
 
Instructions

To claim CME/CMLE credit for the exercise, do the following:

1. Review the Technical Considerations.
2. Click Go to Content and click the first module of the course.
3. Complete the Demographic Survey.
4. Complete the Pre-Test.
5. Review the Educational Activity.
6. Complete and submit the Post Exam. You will have a maximum of three attempts to obtain the required score. You will be notified if you have met the credit requirements after each attempt.
7. Submit the course Evaluation.
8. Enter the maximum number of credits offered and click Claim CME/CMLE to register credit.

Upon completion of this activity, you will be able to:

• Apply the available data and expert recommendations to determine which biomarkers should be assessed in patients with GI malignancies  

• Implement best practices for molecular testing in GI cancers, including the use of tissue-based biomarker testing for evaluation of BRAF V600E, HER2/HER3, BRCA1/2, FGFR2, IDH1, and tumor agnostic markers  

• Plan therapeutic strategies for patients with GI malignancies based on predictive biomarker assessment to improve duration and quality of life  

• Evaluate the clinical validity, utility, and differences among single biomarker companion diagnostics and available comprehensive genomic testing platforms using next-generation sequencing   

• Appraise ongoing clinical trials for novel biomarker-driven treatment strategies in GI malignancies for patient counsel and potential enrollment