During this recorded 2022 ASCP Annual Meeting session, multidisciplinary faculty will discuss the science and latest evidence on emerging biomarkers, resistance mutations, immuno-oncology (I-O) resistance mechanisms, and I-O treatment options (e.g., combination therapy involving CTLA-4 inhibitors) in metastatic NSCLC.  In addition, they will address how to integrate next generation sequencing (NGS) into your biomarker testing workflows and optimize its use for patients.  Finally, they will share best practices in biomarker testing, reporting, and communication to help pathologists and laboratory professionals guide medical oncologists and other team members in the appropriate diagnosis, testing, and treatment for patients.
 
The activity offers 1.0 CME/CMLE credit.
 
The American Society for Clinical Pathology (ASCP) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education (CME) for physicians.

Faculty/Authors

Diana N. Ionescu MD, FRCPC, FCAP
Consultant Pathologist and Medical Lead Anatomical Pathology
Medical Director BC Cervical Cancer Screening Laboratory
Medical Director Clinical Trials, BC Cancer Laboratories
Clinical Professor of Pathology, University of British Columbia
 
Doru Paul, MD, PhD
Attending Physician, Division of Hematology and Medical Oncology
Weill Cornell and New York Presbyterian Hospital 

Physician's Competency: Patient Care, Medical Knowledge.

CME/CMLE Credit: 1.0
Estimated Completion Time: 1.0 hour
Format: Online educational activity

Credit Designation Statement

The ASCP designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only credit commensurate with the extent of their participation in the activity.
 
ASCP designates this enduring material for a maximum of 1.0 CMLE credit.  This activity meets CMP and state re-licensure requirements for laboratory personnel.
 
For questions regarding CME credit, please contact ASCP Customer Service at 1-800-267-2727, during normal business hours: Monday through Friday, 8 a.m. to 6 p.m. Eastern Time

Method of Participation

To complete the activity and receive credit, the participant must complete the online course. CME certificates will be provided on-line.  

Commercial Support
Funded by an independent educational grant from AstraZeneca. 

Instructions

To claim CME/CMLE credit for the exercise, do the following:

1. Review the Technical Considerations.
2. Click Go to Content and click the first module of the course.
3. Complete the Demographic Survey.
4. Complete the Pre-Test.
5. Review the Educational Activity.
6. Complete and submit the Post Exam. You will have a maximum of three attempts to obtain the required score. You will be notified if you have met the credit requirements after each attempt.
7. Submit the course Evaluation.
8. Enter the maximum number of credits offered and click Claim CME/CMLE to register credit.

Upon completion of this activity, you will be able to:

• Describe ongoing investigational efforts regarding emerging biomarkers in metastatic NSCLC

• Utilize NGS to identify current and emerging biomarkers to predict response to personalized therapies for patients with metastatic NSCLC

• Employ strategies for optimizing workflows and turnaround times for NGS

• Discuss the science behind resistance mechanisms in patients with metastatic NSCLC

• Recognize the use of emerging I-O combination therapies and potential biomarkers in patients with metastatic NSCLC

• Develop ways to improve communication among pathologists, oncologists, and other members of the multidisciplinary lung cancer care team