This 30-minute continuing medical education / continuing laboratory medical education (CME/CMLE) credit-bearing, online, on-demand webcast will provide pathologists, laboratory professionals, and other members of the cancer care team with an increased understanding of PD-L1 testing considerations. The on-demand webcast will address the following topics:  

• Recently approved I-O combination therapies and their indications  

• The use of PD-L1 testing as a companion vs complementary diagnostic  

• PD-L1 antibody clones (eg, 22C3, 28-8, SP142), staining protocols, scoring interpretation, and cutoff criteria for approved indications for various cancers  

• Strategies for optimizing the biomarker testing process  

• Best practices in PD-L1 ordering and protocol development  

• PD-L1 testing in combination with other biomarker testing (eg, EGFR and ALK mutations in metastatic or recurrent NSCLC)  

• Testing considerations for limited tissue sample sizes  

• Reporting considerations  

The activity offers 0.5 CME/CMLE credit. 

Faculty/Authors

Dr. Robert Anders, MD, PhD, 
Associate Professor of Pathology, Johns Hopkins University School of Medicine  

Physician's Competency: Patient Care, Medical Knowledge, Practice-Based Learning and Improvement, Professionalism, Systems-Based Practice  

CME/CMLE Credit: 0.5
Estimated Completion Time: 0.5 hour
Format: Online educational activity

Credit Designation Statement

The ASCP designates this enduring material for a maximum of 0.5 AMA PRA Category 1 Credit(s)™. Physicians should claim only credit commensurate with the extent of their participation in the activity. 

ASCP designates this enduring material for a maximum of 1.0 CMLE credit.  This activity meets CMP and state re-licensure requirements for laboratory personnel. 

For questions regarding CME credit, please contact ASCP Customer Service at 1-800-267-2727, during normal business hours: Monday through Friday, 8 a.m. to 6 p.m. Eastern Time 

Method of Participation

To complete the activity and receive credit, the participant must complete the online activity. CME certificates will be provided online.  

Instructions

To claim CME/CMLE credit for the exercise, do the following:

1. Review the Technical Considerations.
2. Click Go to Content and click the first module of the course.
3. Complete the Demographic Survey.
4. Complete the Pre-Test.
5. Review the Educational Activity.
6. Complete and submit the Post Exam. You will have a maximum of three attempts to obtain the required score. You will be notified if you have met the credit requirements after each attempt.
7. Submit the course Evaluation.
8. Enter the maximum number of credits offered and click Claim CME/CMLE to register credit.

Upon completion of this activity, you will be able to:

• Discuss the complexities and limitations associated with different PD-L1 antibody clones, staining protocols, and scoring interpretations 

• Compare and contrast how PD-L1 testing is performed for different cancers and indications 

• Develop strategies to optimize I-O biomarker testing processes 

• Discuss newly approved combinations of I-O therapies and their indications