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ITLPEDUC2404 - CME/CMLE - Newly FDA Approved Alzheimer’s Biomarkers Testing: How to Implement Such Tests in Core Laboratory?
Course Description

Inside the Lab: Newly FDA Approved Alzheimer’s Biomarkers Testing: How to Implement Such Tests in Core Laboratory? 

Activity Description: 

The diagnostic paradigm for Alzheimer's disease (AD) has rapidly shifted in the last five years as fluid-based biomarker testing has emerged as a reliable, accurate, and accessible means to detect amyloid pathology when evaluating a patient for cognitive decline. This podcast is designed to help pathologists and laboratory professionals gain an understanding of plasma testing for markers such as Abeta40/42, P-tau181, and P-tau217 which are rapidly appearing in the commercial space and how healthcare providers have begun incorporating these tests into routine neurology practice. This podcast will help participants to understand the advantages and limitations of these assays as well as their potential application when a physician is evaluating a patient for AD. 

Podcast topics include: 

  • The role of plasma-based biomarker diagnostics in the clinical evaluation of patients with cognitive impairment who are being evaluated for AD  

  • Scientific and clinical considerations for the pathologist when evaluating such plasma-based biomarker assays  

  • Practical considerations for implementing these assays in the clinical laboratory 

Target Audience 

This podcast has been designed to meet the educational needs of pathologists and laboratory professionals.


Faculty/Authors

Amitava Dasgupta, Ph.D.

Professor, Pathology and Laboratory Medicine
The University of Kansas Health System 
University of Kansas, Kansas City, Kansas

Kelsey Woodard, MLS (ASCP)
Chemistry and Special Chemistry Supervisor, Clinical Laboratory 
The University of Kansas Health System
University of Kansas, Kansas City, Kansas 


CME/CMLE Credit: 1.0
Estimated Completion Time: 1 hour
Format: Online Educational Activity

Physician Competencies: Patient Care, Medical Knowledge, Practice-Based Learning, and Improvement 

Accreditation Statement:
The American Society for Clinical Pathology (ASCP) is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education (CME) for physicians. This activity has been planned and implemented in accordance with the Essential Areas and Policies of the Accreditation Council for Continuing Medical Education (ACCME).

Credit Designation Statement 

The ASCP designates this activity for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only credit commensurate with the extent of their participation in the activity.  

ASCP designates this activity for a maximum of 1.0 CMLE credit.  This activity meets CMP and state re-licensure requirements for laboratory personnel.  

For questions regarding CME credit, please contact ASCP Customer Service at 1-800-267-2727, option 2, in the US & Canada or internationally at access code + 3-1-312-541-4890. Monday-Friday, 8am-5pm CT. 

Commercial Support 

This activity is supported by independent educational grants from Lily.  

Instructions

To claim CME/CMLE credit for the exercise, do the following:

  1. Review the Technical Considerations.
  2. Review the Faculty Disclosures.
  3. Click Go to Course to view an overview of the modules in this course.
  4. Click Access to begin the course.
  5. Submit the Demographic Survey.
  6. Review the Educational Activity.
  7. Submit the course Evaluation.
  8. Enter the maximum number of credits offered and click Claim CME to register credit.

Faculty Disclosure

Technical Considerations

Release Date: 10/21/2024
Review Date:
Expiration Date: 10/21/2027

Course Objectives
Following completion of this activity, you will be able to:
  • Explain the basic pathophysiology of Alzheimer’s disease and most recently approved drugs for treatment. 

  • Describe the clinical utility of AD biomarkers and correlation of biomarkers with findings of brain imaging.

  • Discuss commercially available immunoassays for measuring AD biomarkers and implementation in the core lab. 

Summary
Availability: On-Demand
Credit Offered:
1 CME/CMLE Credit
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