ITLPEDUC2601 - CME/CMLE - Inside the Lab Podcast - Advances in NSCLC Biomarker Testing
Course Description

Inside the Lab Podcast - Advances in NSCLC Biomarker Testing 

Biomarker testing has become central to the diagnosis and management of non-small cell lung cancer, yet the rapid expansion of actionable targets and testing technologies has introduced new challenges for pathology and laboratory teams. In this episode, expert panelists reflect on how NSCLC biomarker testing has evolved over the past decade, driven by advances in targeted therapies, next-generation sequencing, and professional practice guidelines. 

The discussion focuses on the clinical relevance of emerging biomarkers, the rationale behind broad molecular profiling, and real-world decision-making around testing strategies and platform selection. Panelists also address practical considerations such as tissue stewardship in small biopsies, coordination across multidisciplinary care teams, and the expanding leadership role of pathologists in ensuring timely, appropriate, and equitable access to biomarker testing for patients with NSCLC

Course topics include: 

  • Evolution of NSCLC biomarker testing and its impact on precision oncology 

  • Current and emerging biomarkers in NSCLC, including HER2, TROP2, and HER3 

  • Laboratory workflows, testing strategies, and tissue stewardship to support comprehensive biomarker assessment 


Faculty/Authors

Ying-Chun Lo, M.D., Ph.D., Associate Professor and Consultant
Divisions of Anatomic Pathology and Laboratory Genetics and Genomics, Department of Laboratory Medicine and Pathology 
Mayo Clinic, Rochester, MN  

Mamatha Chivukula, MD, FASCP
Sutter Health,
San Francisco, California  

CME/CMLE Credit: 0.75
Estimated Completion Time: 0.75 hour
Format: Online Educational Activity

Physician Competencies: Patient Care, Medical Knowledge

Target Audience :
This activity has been designed to meet the educational needs of pathologists and laboratory professionals.  

Accreditation Statement: The American Society for Clinical Pathology (ASCP) is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education (CME) for physicians. This activity has been planned and implemented in accordance with the Essential Areas and Policies of the Accreditation Council for Continuing Medical Education (ACCME).

Credit Designation Statement:

The ASCP designates this activity for a maximum of .75 AMA PRA Category 1 Credit(s)™. Physicians should claim only credit commensurate with the extent of their participation in the activity.   

ASCP designates this activity for a maximum of .75 CMLE credit.  This activity meets CMP and state re-licensure requirements for laboratory personnel.   

For questions regarding CME credit, please contact ASCP Customer Service at 1-800-267-2727, option 2, in the US & Canada or internationally at access code + 3-1-312-541-4890. Monday-Friday, 8am-5pm CT. 

Method of Participation:
To complete the activity and receive credit, the participant must participate in the online activity. CME certificates will be provided online.  

Commercial Support:
This activity is supported by independent educational grants from AstraZeneca Pharmaceuticals and Daiichi Sankyo, Inc.  

Instructions

To claim CME/CMLE credit for the exercise, do the following:

  1. Review the Technical Considerations.

  2. Review the Faculty Disclosures.

  3. Click Go to Course to view an overview of the modules in this course.

  4. Click Access to begin the course and complete the Demographic Survey.

  5. Review the Educational Activity.

  6. Submit the course Evaluation.

  7. Enter the maximum number of credits offered and click Claim CME to register credit

Faculty Disclosure

Technical Considerations

Release Date: 1/9/2026 
Review Date:
Expiration Date: 1/9/2029 

Course Objectives
Following completion of this activity, you will be able to:
  • Discuss current and emerging biomarkers for NSCLC and their relevance to evolving targeted therapies

  • Identify practice guideline–recommended approaches to biomarker testing and testing strategy selection in NSCLC 

  • Apply practical specimen-handling and laboratory workflow strategies to optimize tissue utilization and support comprehensive, equitable biomarker testing

Summary
Availability:
On-Demand
Credit Offered:
0.75 CME/CMLE Credit
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