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LQCL2202 - CMLE - LIMITATIONS OF IMMUNOASSAYS AND LIQUID CHROMATOGRAPHY– TANDEM MASS SPECTROMETRY SCREEN AND CONFIRM TESTING
Course Description

LabQ 2022 Clinical Laboratory: Clinical Chemistry  

Faculty/Authors

KYLE LUND, PHD
ROBERT L. FITZGERALD, PHD, DABCC 

DEPARTMENT OF PATHOLOGY
UNIVERSITY OF CALIFORNIA SAN DIEGO
San Diego, California 


CMLE Credit: 2.0
Estimated Completion Time: 2 hour
Format: Online Educational Activity and Post Exam

Instructions

To claim CMLE credit for the exercise, do the following:

  1. Review the Technical Considerations.
  2. Click Go to Course to view an overview of the modules in this course.
  3. Click Access to begin the course.
  4. Review the Educational Activity.
  5. Complete and submit the Post Exam.
  6. Submit the course Evaluation to register your credit.

Faculty Disclosures​
The faculty have no relevant financial relationships with commercial interests to disclose.

Technical Considerations

Release Date: 05/27/2022 
Review Date:
Expiration Date: 12/31/2024 

Course Objectives
Following completion of this activity, you will be able to:
  • describe the limitations of immunoassays and liquid chromatography–tandem mass spectrometry (LC-MS/MS) screen and confirm approaches for urine drug testing; 

  • describe the process for identifying unknown synthetic drugs in a urine sample; 

  • explain the difference between high-resolution and low-resolution MS; 

  • identify compounds that contain chlorine and bromine based on A+2 MS signatures; and 

  • describe the process used to improve chromatographic peak resolution when challenged with coeluting compounds. 

Summary
Availability: On-Demand
Credit Offered:
2 CMLE Credits
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