LabQ 2022 Clinical Laboratory: Clinical Chemistry Faculty/Authors
KYLE LUND, PHDROBERT L. FITZGERALD, PHD, DABCC
DEPARTMENT OF PATHOLOGYUNIVERSITY OF CALIFORNIA SAN DIEGOSan Diego, California
CMLE Credit: 2.0 Estimated Completion Time: 2 hour Format: Online Educational Activity and Post Exam
Instructions
To claim CMLE credit for the exercise, do the following:
Faculty DisclosuresThe faculty have no relevant financial relationships with commercial interests to disclose.
Technical Considerations
Release Date: 05/27/2022 Review Date:Expiration Date: 12/31/2024
describe the limitations of immunoassays and liquid chromatography–tandem mass spectrometry (LC-MS/MS) screen and confirm approaches for urine drug testing;
describe the process for identifying unknown synthetic drugs in a urine sample;
explain the difference between high-resolution and low-resolution MS;
identify compounds that contain chlorine and bromine based on A+2 MS signatures; and
describe the process used to improve chromatographic peak resolution when challenged with coeluting compounds.