LabQ 2022 Clinical Laboratory: Molecular Diagnostics Exercise  

Faculty/Authors
MEGAN SWEENEY, MLS(ASCP) MB
CIRCULOGENE THERANOSTICS
Pensacola, Florida  

CMLE Credit: 2.0
Estimated Completion Time: 2 hour
Format: Online Educational Activity and Post Exam

Instructions

To claim CMLE credit for the exercise, do the following:

1. Review the Technical Considerations.
2. Click Go to Course to view an overview of the modules in this course.
3. Click Access to begin the course.
4. Review the Educational Activity.
5. Complete and submit the Post Exam.
6. Submit the course Evaluation to register your credit.

Faculty Disclosures​
The faculty have no relevant financial relationships with commercial interests to disclose.

Technical Considerations

Release Date: 05/27/2022 
Review Date:
Expiration Date: 12/31/2024 

• explain the inheritance pattern of Lynch syndrome and the likelihood of passing from one generation to the next;  

• differentiate the proteins involved in the mismatch repair system based on their roles in the process; 

• illustrate the expected results of a microsatellite stable (MSI-S) and a MSI-high (MSI-H) capillary electrophoresis run; 

• discuss the correlation of MSI/immunohistochemistry (IHC) results with those genes for Lynch syndrome detected via next-generation sequencing; and 

• describe the clinical utility of IHC and MSI test results even if the patient does not have Lynch syndrome.