LabQ 2023 Clinical Laboratory: Transfusion Medicine 

Faculty/Authors
ANDREA P. HO, MD 
BETHANY E. HO, BA
NICOLE L. DRAPER, MD
​
UNIVERSITY OF COLORADO SCHOOL OF MEDICINE
Aurora, Colorado 

CMLE Credit: 2.0
Estimated Completion Time: 2 hour
Format: Online Educational Activity and Post Exam

Instructions

To claim CMLE credit for the exercise, do the following:

1. Review the Technical Considerations.
2. Click Go to Course to view an overview of the modules in this course.
3. Click Access to begin the course.
4. Review the Educational Activity.
5. Complete and submit the Post Exam.
6. Submit the course Evaluation to register your credit.

Faculty Disclosures​
The faculty have no relevant financial relationships with commercial interests to disclose.

Technical Considerations

Release Date: 05/27/2023 
Review Date:
Expiration Date: 12/31/2025 

• discuss a case of a strongly positive Kleihauer-Betke test (KBT);  

• identify challenges of KBT interpretation and implications of dosage and administration of Rho(D) immune globulin (RhIg) based on KBT results; 

• identify consequences of Rh isoimmunization and the importance of antepartum RhIg;  

• calculate proper dosages of RhIg to administer postpartum; 

• introduce use of the erythrocyte rosette screening test, confirmatory KBT, and flow cytometry studies to identify and quantify fetomaternal hemorrhage; 

• identify causes of false-positive and false-negative results and concepts of underestimation and overestimation when using the KBT; and 

• suggest strategies for medically treating a patient with a high KBT value.