LabQ 2023 Clinical Laboratory: Transfusion Medicine Faculty/Authors ANDREA P. HO, MD BETHANY E. HO, BANICOLE L. DRAPER, MDUNIVERSITY OF COLORADO SCHOOL OF MEDICINEAurora, Colorado CMLE Credit: 2.0 Estimated Completion Time: 2 hour Format: Online Educational Activity and Post Exam
Instructions
To claim CMLE credit for the exercise, do the following:
Faculty DisclosuresThe faculty have no relevant financial relationships with commercial interests to disclose.
Technical Considerations
Release Date: 05/27/2023 Review Date:Expiration Date: 12/31/2025
discuss a case of a strongly positive Kleihauer-Betke test (KBT);
identify challenges of KBT interpretation and implications of dosage and administration of Rho(D) immune globulin (RhIg) based on KBT results;
identify consequences of Rh isoimmunization and the importance of antepartum RhIg;
calculate proper dosages of RhIg to administer postpartum;
introduce use of the erythrocyte rosette screening test, confirmatory KBT, and flow cytometry studies to identify and quantify fetomaternal hemorrhage;
identify causes of false-positive and false-negative results and concepts of underestimation and overestimation when using the KBT; and
suggest strategies for medically treating a patient with a high KBT value.