LabQ 2024 Clinical Laboratory: Molecular Diagnostics Faculty/Authors Delecia R. Robinson, MDSenior Medical Director, Laboratory Medicine (Molecular and Non-molecular)eviCore HealthcareBluffton, South Carolina CMLE Credit: 2.0 Estimated Completion Time: 2 hour Format: Online Educational Activity and Post Exam
Default Credit Type: None (You must meet the eligibility requirements in order to obtain CME or SAMs CME credit.)
Instructions
To claim CMLE credit for the exercise, do the following:
Faculty DisclosuresThe Journal CME editor and faculty have no relevant financial relationships with commercial interests to disclose.
Technical Considerations
Release Date: 03/31/2024Review Date:Expiration Date: 12/31/2026
briefly describe the workflow for next-generation sequencing of paraffin-embedded tumor samples;
list several tumor mutations and the associated drug class that may (or may not) be used to treat them;
contrast the clinical implications of monoallelic and biallelic MUTYH mutations;
describe the testing required to determine if a mutation identified by a next-generation sequencing tumor marker panel is a germline mutation; and
discuss the increased cancer risks associated with MUTYH-associated polyposis hereditary cancer syndrome.