LQCL2513 - CMLE - An Unusual JAK2 Mutation Affects the Detection Sensitivity of Allele-Specific Quantitative Polymerase Chain Reaction (AS-qPCR) Assay

Course Description

LabQ 2025 Clinical Laboratory: Molecular Pathology

Faculty/Authors

Linsheng Zhang, MD, PhD
Associate Professor

Emory University School of Medicine
Atlanta, Georgia

CMLE Credit: 2.0

Estimated Completion Time: 2 hour

Format: Online Educational Activity and Post Exam

Instructions

To claim CMLE credit for the exercise, do the following:

Review the Technical Considerations.
Click Go to Course to view an overview of the modules in this course.
Click Access to begin the course.
Review the Educational Activity.
Complete and submit the Post Exam.
Submit the course Evaluation to register your credit.

Faculty Disclosures
The faculty have no relevant financial relationships with commercial interests to disclose.

Technical Considerations

Release Date: 5/31/2025
Review Date:
Expiration Date: 12/31/2027

Course Objectives

Following completion of this activity, you will be able to:

list the common driver mutations in myeloproliferative neoplasms (MPN);

discuss the pathophysiology of the most common MPN mutations;

explain the allele-specific quantitative polymerase chain reaction (AS-qPCR) for single nucleotide mutation detection; and

explain how to follow up on the unusual result from single gene mutation tests.

Summary

Availability:

On-Demand

Credit Offered:

2 CMLE Credits