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LQCL2601 - CMLE - Pheochromocytoma: Preanalytical Factors That Shape Test Results
Course Description

LabQ 2026 Clinical Laboratory: Clinical Chemistry 
 
Faculty/Authors

Nadine Lerret, PhD, MLS (ASCP)CM
Rush University
Chicago, Illinois 

CMLE Credit: 2.0

Estimated Completion Time: 2 hour

Format: Online Educational Activity and Post Exam

Instructions

To claim CMLE credit for the exercise, do the following:

  1. Review the Technical Considerations.
  2. Click Go to Course to view an overview of the modules in this course.
  3. Click Access to begin the course.
  4. Review the Educational Activity.
  5. Complete and submit the Post Exam.
  6. Submit the course Evaluation to register your credit.

Faculty Disclosures​
The faculty have no relevant financial relationships with commercial interests to disclose.

Technical Considerations

Release Date: 3/31/2026 
Review Date:
Expiration Date: 12/31/2028  

Course Objectives
Following completion of this activity, you will be able to:

  • analyze the biochemical markers and laboratory values characteristic of pheochromocytoma, including plasma and urinary catecholamines and metanephrines, while critically evaluating how pre-analytical factors (particularly patient anxiety during specimen collection) can affect test results and interpretation; 

  • evaluate the role of high-performance liquid chromatography-mass spectrometry (HPLC-MS) in minimizing pre-analytical interferences and improving the quantification of catecholamines and metanephrines; 

  • discuss where genetic testing fits into diagnosis and management of pheochromocytoma; and 

  • explain how the catecholamines produced in excess by pheochromocytomas contribute to the most common symptoms of this tumor. 
Summary
Availability:
On-Demand
Credit Offered:
2 CMLE Credits
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