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LQCL2603 - CMLE - Laboratory Evaluation of Isolated ALP Elevation: A Case Study Highlighting the Role of Bone Turnover Markers
Course Description

LabQ 2026 Clinical Laboratory: Clinical Chemistry 
 
Faculty/Authors

Kristen Ciano, MBA, MS, MLS (ASCP)CM 
Manager, Scientific Affairs
Icon Central Laboratory
Farmingdale, New York 

CMLE Credit: 2.0

Estimated Completion Time: 2 hour

Format: Online Educational Activity and Post Exam

Instructions

To claim CMLE credit for the exercise, do the following:

  1. Review the Technical Considerations.
  2. Click Go to Course to view an overview of the modules in this course.
  3. Click Access to begin the course.
  4. Review the Educational Activity.
  5. Complete and submit the Post Exam.
  6. Submit the course Evaluation to register your credit.

Faculty Disclosures​
The faculty have no relevant financial relationships with commercial interests to disclose.

Technical Considerations

Release Date: 3/31/2026 
Review Date:
Expiration Date: 12/31/2028  

Course Objectives
Following completion of this activity, you will be able to

  • differentiate sources of total alkaline phosphatase elevation; 

  • summarize the pathophysiology, clinical features, and complications of Paget disease; 

  • describe key bone turnover markers and their role in diagnosis and monitoring; and 

  • explain treatment approaches and monitoring therapy responses for Paget disease. 
Summary
Availability:
On-Demand
Credit Offered:
2 CMLE Credits
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