1. Catalog
  2. LQCL2611 - CMLE - Diagnosing a Culture-Negative In ...
LQCL2611 - CMLE - Diagnosing a Culture-Negative Infection with Targeted Next-Generation Sequencing
Course Description

LabQ 2026 Clinical Laboratory: Microbiology 
 
Faculty/Authors

Michelle Luu, BS  

Rebecca Yee, PhD, D(ABMM), M(ASCP)CM 

 
Department of Pathology
George Washington University School of Medicine and Health Science
Washington, D.C. 

CMLE Credit: 2.0

Estimated Completion Time: 2 hour

Format: Online Educational Activity and Post Exam

Instructions

To claim CMLE credit for the exercise, do the following:

  1. Review the Technical Considerations.
  2. Click Go to Course to view an overview of the modules in this course.
  3. Click Access to begin the course.
  4. Review the Educational Activity.
  5. Complete and submit the Post Exam.
  6. Submit the course Evaluation to register your credit.

Faculty Disclosures​
The faculty have no relevant financial relationships with commercial interests to disclose.

Technical Considerations

Release Date: 3/31/2026 
Review Date:
Expiration Date: 12/31/2028  

Course Objectives
Following completion of this activity, you will be able to

  • describe the diagnostic workup of infections in cerebrospinal fluid (CSF); 

  • discuss different molecular approaches and their limitations for detection of microorganisms in CSF; 

  • explain the differences between whole-genome sequencing, amplicon-targeted next-generation sequencing (NGS), and metagenomics sequencing; and 

  • describe a pathogen that is heavily implicated in abscess formation. 

 
 
Summary
Availability:
On-Demand
Credit Offered:
2 CMLE Credits
Powered By