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LQHS2605 - CMLE - Evaluation of Bone Invasion in Oral Squamous Cell Carcinoma
Course Description

LabQ 2026 Clinical Laboratory: Histology 

Faculty/Authors

Ying-Hsia Chu, MD 

Department of Laboratory Medicine and Pathology
University of Minnesota, Twin Cities
Minneapolis, Minnesota

CMLE Credit: 2.0

Estimated Completion Time: 2 hour
Format: Online Educational Activity and Post Exam

Instructions

To claim CMLE credit for the exercise, do the following:

  1. Review the Technical Considerations.
  2. Click Go to Course to view an overview of the modules in this course.
  3. Click Access to begin the course.
  4. Review the Educational Activity.
  5. Complete and submit the Post Exam.
  6. Submit the course Evaluation to register your credit.

Faculty Disclosures​
The faculty have no relevant financial relationships with commercial interests to disclose.

Technical Considerations

Release Date:  4/30/2026   
Review Date:
Expiration Date: 12/31/2028 

Course Objectives
Following completion of this activity, you will be able to:

  • recognize the importance of accurate bone specimen processing in staging oral squamous cell carcinoma (OSCC), particularly for the assessment of medullary bone invasion; 

  • identify specific technical challenges that compromise diagnostic accuracy, including bone fragmentation, difficulties in visualizing the cortico-medullary junction, and processing artifacts that lead to interobserver variability; 

  • understand the anatomical variations of mandibular bone structure and how these anatomical features influence specimen handling and sectioning strategies; and 

  • apply best practices for bone specimen processing including appropriate decalcification and sectioning approaches to minimize artifacts and ensure diagnostic accuracy.  

Summary
Availability:
On-Demand
Credit Offered:
2 CMLE Credits
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