LabQ 2022 Clinical Laboratory: Phlebotomy Bonus Clinical Laboratory Exercise (Molecular Diagnostics) Faculty/Authors
MEGAN SWEENEY, MLS(ASCP) MB
CIRCULOGENE THERANOSTICSPensacola, Florida CMLE Credit: 2.0 Estimated Completion Time: 2 hour Format: Online Educational Activity and Post Exam
Instructions
To claim CMLE credit for the exercise, do the following:
Faculty DisclosuresThe faculty have no relevant financial relationships with commercial interests to disclose.
Technical Considerations
Release Date: 7/5/2022 Review Date:Expiration Date: 12/31/2024
explain the inheritance pattern of Lynch syndrome and the likelihood of passing from one generation to the next;
differentiate the proteins involved in the mismatch repair system based on their roles in the process;
illustrate the expected results of a microsatellite stable (MSI-S) and a MSI-high (MSI-H) capillary electrophoresis run;
discuss the correlation of MSI/immunohistochemistry (IHC) results with those genes for Lynch syndrome detected via next-generation sequencing; and
describe the clinical utility of IHC and MSI test results even if the patient does not have Lynch syndrome.