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VPGRAPCP2402 - CME/CMLE - A Practical Diagnostic Approach to Neonatal Cholestasis
Course Description

Neonatal cholestasis includes a myriad of disorders characterized by conjugated hyperbilirubinemia with their early recognition being crucial in their treatment and prognosis. The leading cause of neonatal cholestasis is biliary atresia which is the most common indication for pediatric liver transplantation worldwide. During the workup of these patients one of the crucial components is the evaluation of liver biopsies which in the hands of an experienced pathologists has a positive predictive value for biliary atresia of ~90%. The histologic changes in these biopsies can be grouped in three histologic patterns: obstructive, neonatal hepatitis (giant cell hepatitis) and bile duct paucity. Each one of these patterns is associated with several important diagnostic considerations. In this virtual grand round, we will discuss a practical approach to these challenging biopsies with an emphasis in grouping these cases in one of those histologic groups particularly the obstructive pattern given its treatment implications.  

Faculty/Authors

Ivan Gonzalez, MD  

Physician Competencies: Medical knowledge


CME/CMLE Credit: 1.0
Estimated Completion Time: 1 hour
Format: Online Educational Activity

Accreditation Statement:
The American Society for Clinical Pathology (ASCP) is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education (CME) for physicians. This activity has been planned and implemented in accordance with the Essential Areas and Policies of the Accreditation Council for Continuing Medical Education (ACCME).

Credit Designation Statement: The American Society for Clinical Pathology (ASCP) designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Instructions

To claim CME/CMLE credit for the exercise, do the following:

  1. Review the Technical Considerations.
  2. Review the Faculty Disclosures.
  3. Click Go to Course to view an overview of the modules in this course.
  4. Click Access to begin the course.
  5. Submit the course Evaluation.
  6. Enter the maximum number of credits offered and click Claim CME to register credit.

Faculty Disclosures

Technical Considerations

Release Date: 12/04/2024
Review Date:
Expiration Date: 12/04/2027 

Summary
Availability: On-Demand
Credit Offered:
1 CME/CMLE Credit
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