AJSP2402 - CME/CMLE - CME/CMLE - Current gross examination and reporting patterns of post–neoadjuvant chemotherapy cystectomy specimens-Current gross examination and reporting patterns of post–neoadjuvant chemotherapy cystectomy specimens

Current gross examination and reporting patterns of post–neoadjuvant chemotherapy cystectomy specimens

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The article discusses the need for a standardized approach in the gross examination and reporting of post-neoadjuvant chemotherapy (NACT) cystectomy specimens for bladder cancer. Neoadjuvant chemotherapy is often used for muscle-invasive bladder cancer, leading to cases where no gross lesions are identifiable post-treatment. The study surveyed pathologists and pathologists' assistants to evaluate current practices and found inconsistencies, especially when no gross lesions were present. The majority of respondents supported the implementation of standardized protocols to address these inconsistencies.<br /><br />Key findings include that identifying gross tumors occurred less frequently than identifying tumor beds or ulcer beds. Respondents typically recommended submitting gross tumor in 1 block per centimeter and tumor beds entirely. However, there was more variability in handling cases with no gross lesions. Pathologists and PAs generally agreed on practices when gross lesions were present but differed in approaches for cases without gross lesions.<br /><br />The study highlights the importance of addressing the lack of standardization in the examination and reporting of post-NACT cystectomy specimens. It emphasizes the need for guidelines to streamline practices and improve the consistency of handling these challenging cases. Overall, the majority of respondents expressed support for implementing a standardized approach to gross examination and reporting for post-NACT cystectomy specimens.

Keywords

Standardized approach

Gross examination

Post-neoadjuvant chemotherapy

Cystectomy specimens

Bladder cancer

Pathologists

Pathologists' assistants

Inconsistencies

Standardized protocols

Gross lesions